MOS5425 Full course - January 2018

Asked by julia
Dated: 9th Feb'18 10:25 PM
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Unit 1 discussion

Introduce yourself to your classmates with your name, location, current employment, and future goals. In the event of a natural disaster such as Hurricane Matthew in 2016 or Hurricane Katrina in 2005, identify and explain which two specialized fields of toxicology would be most involved in assessing the health risks and environmental issues involved in the aftermath of the storms. What do you think their main role would be?

 

Unit 2 discussion

More states in the United States are legalizing the use of medicinal marijuana. Some states have laws that classify a person as being impaired to drive if an illegal substance or its metabolites are in the body. Marijuana, when it undergoes biotransformation, metabolizes into two different metabolites, Hydroxy-THC and Carboxy-THC. The first causes adverse effects (e.g., decreased motor coordination, lethargy, slurred speech, and dizziness) while the second, although it does not cause impairment, stays in the body for an extended period of time. Consider how marijuana's biotransformation may vary depending on the individual and the varying ability of marijuana's metabolites to cause impairment. Do you think that laws that prosecute regardless of the type of metabolite are justified to prosecute for a driving while intoxicated (DWI)? Why, or why not?

 

Unit 3 discussion

In 2013, the FDA set limits for arsenic in apple juice. In 2016, the FDA proposed a limit for arsenic in infant rice cereal. Consider the toxicological effects of arsenic on the body. Discuss what types of food are more likely to contain arsenic? What do you feel are the main concerns regarding digestion of these foods and the effects they could have on the body? Is the FDA sufficiently protecting the food supply in the United States from arsenic concerns? Why, or why not?

 

Unit 4 discussion

Carbon footprint is a term used to describe the impact an individual has on the release of carbon compounds, including carbon dioxide, into the environment. This carbon footprint is commonly produced by the burning of fossil fuels. With the burning of fossil fuels comes the release of many pollutants that cause health concerns, such as the release of particulate matter on the respiratory system. Reflect on individuals you know with respiratory, immune, or hepatic system concerns. How can the environmental toxicants affect their health? Whose responsibility do you think it should be to see that the carbon footprint from our community is reduced to minimize adverse health effects?

 

 

 

Unit 5 discussion

The skin is one of the largest organs of the body. It is also the body's first line of defense for protection against foreign agents and toxicants. Recall a time that you encountered an acute or chronic skin reaction from an environmental toxicant from the region in which you reside. What were the main symptoms of exposure? If you have never had such an experience, then discuss an environmental or industrial toxicant that is present in the region where you reside that may cause toxicity to the skin and the symptoms that might be expected. What do you think are the most effective safeguards against exposure to this toxicant?

 

 

Unit 6 discussion

We have examined toxicants that affect various systems of the body. What are your thoughts on biological warfare agents? Why do you think this type of toxicant is used? Do you think they are needed? What are some of the effects of these chemicals? With respect for your peers thoughts, provide your perspective on biological warfare.

Please include the name of the person or question to which you are replying in the subject line. For example, "Tom's response to Susan's comment."

 

Unit 7 discussion

Household cleaning products are some common solvents that you may be in contact with on a regular basis. Based on what you have learned about solvents, discuss what you feel is the most dangerous solvent that you commonly use. Do you think the cleaning product label properly warns you of the toxic effects of the solvent? What are some of the side effects of toxicity of the solvent? Why do you think this product is more toxic than other cleaning products that you come in contact with?

Please include the name of the person or question to which you are replying in the subject line. For example, "Tom's response to Susan's comment."

 

Unit 8 discussion

Identify a task that you would need to perform in your current career or future career, and explain how you would apply the knowledge you have learned in this course to succeed at performing the task in a real-word scenario.

Please include the name of the person or question to which you are replying in the subject line. For example, "Tom's response to Susan's comment."

 

 

 

 

Unit I PowerPoint Presentation

Assume the role of an environmental safety expert who is presenting to a group of undergraduate college students about the application of toxicology in the field of environmental health and safety. Your presentation should address the following key points.

Explain how dose-response data are utilized for risk assessment.

Discuss the relationship between risk assessment and risk management.

Identify and explain how at least three fields of toxicology contribute to areas of environmental safety and health.

Research and discuss one current event (within the last six to eight months) that exemplified the relationship between toxicology and environmental safety and health.

The assignment should be completed as a PowerPoint presentation and should meet the following requirements:

1. The length should be at least eight slides, not including your title and reference slides.

2. Key points only should be entered on slides. Full paragraphs should not be included on presentation slides.

3. Voiceover or speaker notes should be included for details of the discussion. This should not be an exact replica of the

slide information but an expansion of information to fill in the blanks and provide additional details to the audience.

4. Include least three visual aids and/or graphics.

5. A minimum of three credible sources should be used for this assignment, and the references should be properly cited in a reference list at the end of the PowerPoint. The CSU Online Library is a great place to find credible sources. If you need any assistance, we have a full staff of librarians available to help you get started with research. If you need any

assistance creating your PowerPoint, click here for a Writing Center tutorial that covers best practices for creating effective PowerPoint presentations. All references and citations used must be in APA style.

Information about accessing the grading rubric for this assignment is provided below.

 

Unit II Research Paper

Pesticides are a common environmental concern due to the potential long-term effects of the chemicals and their metabolites on the immediate environment and ecosystem. For this assignment, research a common pesticide and write a three-page research paper that includes the following components:

1. Identify the main active ingredient of the pesticide and how the pesticide is used.

2. Identify and describe which of the four cornerstones of xenobiotic pharmacokinetics are affected in the way the pesticide works to kill the targeted organism.

3. Identify the metabolites of the active ingredient of the pesticide, and discuss the toxicity and lifespan of the metabolites. Be sure to address the cornerstone processes associated with xenobiotic metabolism of the pesticide through the body.

4. Provide your thoughts on whether or not this pesticide is safe for the overall ecosystem in the manner it is used and the resulting effects of its application as it breaks down into its metabolites. Can this biotransformation result in toxicity?

The assignment should be completed as a text document and should meet the following requirements:

1. The discussion should include the four aspects of the assignment as outlined above.

2. The paper should be at least three pages in length, not including the title or reference page. Use proper APA

MOS 5425, Advanced Toxicology 2

formatting for all citations and references.

3. A minimum of three credible references should be used for this assignment, and the references should be properly cited in the text as well as in a reference list.

Information about accessing the grading rubric for this assignment is provided below.

 

Unit III Case Study

In this assignment, you will choose options from each category to design your own case study. Once you have selected one option from each category, you will use that profile to write a case study report. Do not use the same chemical you researched in Unit II. Be creative in developing your character by giving a name, occupation (if applicable), identity, and description of the individual and the situation and circumstances of the case study. The details of the effects of the chemical exposure should be supported by your references.

Step 1: Identify a specific chemical from ONE of these categories:

a. fungicide,

b. rodenticide,

c. herbicide, or

d. insecticide.

Step 2: Choose a profile of the individual affected:

a. adult or

b. child.

Step 3: Research at least two incidents of exposure of the chemical.

Step 4: Develop a case study of exposure of your chemical to the individual. Discuss the following in your case study:

1. Identify how the individual was exposed to the chemical.

2. Identify the exposure pathway of your chosen chemical.

3. What organ systems were affected by the chemical?

4. What acute and chronic effects of exposure to the chemical were observed? Would the effects have been different if the individual was younger or older?

5. How could exposure to the chemical be avoided?

The case study should include the following components:

1. Include all of the aspects in Step 4.

2. Utilize at least three credible references, one of which may be the textbook, and one of which must come from the CSU Online Library.

3. Include a minimum of at least two pages, not including title and reference pages.

4. All sources used, including the textbook, must be referenced; paraphrased and quoted material must have accompanying citations. All references and citations used must be in APA style.

Information about accessing the grading rubric for this assignment is provided below.

 

Unit IV Research Paper

Research and identify an environmental or occupational toxicant that effects either the respiratory, immune, or hepatic system. Research and discuss the following:

1. Explain the normal function of the system and what makes it susceptible to toxicity.

2. Describe how exposure to the toxicant is possible.

3. Analyze the acute and/or chronic effects of the toxicant.

4. Describe recent concerns about the toxicant (within the last two years) and any actions taken to reduce the toxicant in the environment or reduce occupational exposure to the toxicant.

Your research paper should meet the following requirements:

1. Address all of the above mentioned aspects in the discussion.

2. The paper should be a minimum of three pages in length, not including title and reference pages.

3. Utilize at least four credible references no more than five years old.

4. Utilize proper APA formatting and citations.

Information about accessing the grading rubric for this assignment is provided below.

 

Unit V Article Critique

In the CSU Online Library, locate a research article that discusses an industrial or environmental toxicant that causes nephrotoxicity. The article that you review should be at least two pages in length and no more than five years old. The Academic OneFile database in the CSU Online Library is a great place to begin your research. Review the article and briefly summarize the purpose for the study. The discussion should include the following:

1. Include a summary of the purpose of the research and the research findings.

2. Discuss how the findings of at least two other articles support or contradict the findings of the main article. MOS 5425, Advanced Toxicology 3

3. Discuss how this information might be useful in the field of safety.

Your critique should be at least three pages in length, not including title and reference pages. The article critique should include a minimum of three sources, including the article you review as well as the textbook. Use APA format for your critique, including all references and in-text citations.

Information about accessing the grading rubric for this assignment is provided below.

 

Unit VI Research Paper

In the assigned reading for this unit, you learned about various chemicals that induce reproductive toxicity. Not limiting yourself to the chemicals that are mentioned in the assigned reading, identify a toxicant that causes reproductive toxicity.

Develop a research paper that includes the following:

1. background information on the toxicant, its use, and routes of exposure;

2. the process by which this toxicant causes reproductive toxicity and the concentration of exposure;

3. ways exposure to the toxicant might be limited, treated, and/or effects reversed; and

4. recent research findings (within the last five years) on this toxicant.

The research paper should be a minimum of three pages in length, not including the title and reference pages, and written in APA format with proper in-text citations and references. The paper should utilize at least three credible sources that include at least one peer reviewed journal article published within the last five years.

Information about accessing the grading rubric for this assignment is provided below.

 

 

Unit VII PowerPoint Presentation

Metals are basic elements that do not degrade any further, so they are able to persist in the environment. Metals may not always stay in the same form because they are able to react to form different compounds. Research a metal that was discussed in the textbook reading such as mercury, arsenic, or cadmium. Create a PowerPoint presentation at least seven

slides in length, discussing the following:

background information on the metal,

the cornerstone xenobiotic pharmacokinetic properties and effects of the metal,

the bioaccumulative effects of the metal in the environment and how it affects humans and the environment, and concentration of metal that is considered toxic and symptoms of toxicity by this metal.

Your PowerPoint should be a cumulation of what you have learned throughout the course. For instance, if the metal has particular effects on a certain body system or organ, be sure to give information about these effects. The assignment should meet the following requirements:

The length should be a minimum of seven slides, not including your title and reference slides.

Use speaker notes to explain the key points that are provided in the slides.

Include least two visual aids and/or graphics.

A minimum of two credible sources should be used for this assignment, and the references should be properly cited in a reference list at the end of the PowerPoint.

Information about accessing the grading rubric for this assignment is provided below.

 

 

 

 

Unit VIII Scholarly Activity

Research a carcinogen that can be classified as either an environmental or occupational toxicant that has had relevance in the news within the last five years.

In your paper, analyze and briefly summarize the situation that brought the carcinogen to newsworthy status. Discuss the exposure limits of this carcinogen, and how individuals were exposed. Also, discuss the toxicological effects that were not only observed, but all of the possible effects of this agent. In referencing Chapter 23 from your assigned reading, briefly discuss the models used for assessing cancer risks.

Your analysis should be at least three pages in length. The title page and reference page are not included in the required paper length. Your paper must contain at least three references and may include reliable internet sources, books, and professional journals or resources related to the profession. All sources used, including the textbook, must be referenced; paraphrased and quoted material must have accompanying citations.

Information about accessing the grading rubric for this assignment is provided below.

MOS5425 Full course - January 2018
Answered by julia
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Dated: 9th Feb'18 10:25 PM
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